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An established and proven processing technology in the pharmaceutical industry, spray-drying has been shown to improve bioavailability of poorly soluble compounds. By co-precipitating API with a polymer in a stable amorphous solid dispersion, spray-drying improves dissolution rates and enhances the bioavailability of poorly soluble compounds. Additionally, for high dose drugs, spray-drying can improve drug loading and reduce tablet size by improving compression properties of resulting powders.
A widely used processing technology, spray-drying offers a number of advantages over conventional multi-step processes and particle reduction technologies: